Disrupted the formation of red blood cells

TREATMENT ... the children living with thalassemia undergoing blood transfusion .
TREATMENT … children living with thalassemia undergoing blood transfusion.

WE are often reminded to undergo HIV testing before marriage partner, but have you ever thought of thalassemia testing

Yes, thalassemia testing is also important for couples to be married in order to avoid infection and thalassemia major birth.

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    DETECTION … Blood tests can identify carriers of thalassemia in the early stages.

estimated 780,000 to 1.3 million people in Malaysia and 120 carriers of this genetic thalassemia major and 350 babies born each year.

Consultant Haematology Coast Hospital Kuala Lumpur, Datuk Dr Vijaya Cage Jaganathan Naidu, said that thalassemia is a genetic disease that interfere with the formation of red blood cells, red blood normal.Sel patients easily damaged and will produce iron materials are concentrated in several vital organs like heart, brain, liver and kidneys, and broke it.

“thalassemia patients often suffer from low hemoglobin level (anemia) and requires continuous blood transfusion.

“It is a genetic disease or hereditary, in which children have thalassemia gene from a parent. It is not a contagious disease that can not be transmitted through blood, air, water or physical contact. Men and women have equal opportunity to get this disease, “he said recently.

He said there are two types of thalassemia thalassemia minor (thalassemia gene carriers) and thalassemia major (thalassemia sufferers).” br />
“thalassemia gene carriers showed no health problems but a thalassemia gene carriers of thalassemia gene can be put down to children.

” People with thalassemia major showed signs since the age of three to 18 months. Among the symptoms the body is weak and restless, trouble breathing, stomach due to swelling of the liver and spleen, poor growth and no change in formation on the face when the child grows.

“Most importantly, public awareness of the disease is still is low. They need to be more sensitive and have a blood test if the family is a carrier of thalassemia. If you get treatment and advice, it might have been avoided, “he said.

/> Thalassemia type
/> There are two types of thalassemia:

  • thalassemia minor – Refers to the carrier or those with thalassemia gene defect but no sign.

  • thalassemia major – People who have thalassemia genes in full and signs.

    /> thalassemia carriers in Malaysia
    /> usually thalassemia sufferers do not show any signs or other health problems. Detection of thalassemia genes can only be revealed to him. If the parent is a carrier, the following conditions may occur.

    /> Percentage risk for each pregnancy:
    />

  • 50 per cent probability that carriers
    />
  • 50 percent of normal possibility />
  • No child who is suffering from thalassemia (thalassemia major)


    People with thalassemia
    /> If both parents are carriers, the following conditions may occur;
  • 25 per cent chance of their children suffering from thalassemia />
  • 50 per cent probability that their child is a carrier
    />
  • 25 per cent chance the child
    normal /> (Note: Patients of thalassemia usually have a low hemoglobin level of less than 10g/dl) />

    Signs and symptoms of thalassemia />
    thalassemia carrier usually appears normal child during birth. However, they began to experience severe anemia between the ages of 13 to 18 months.

  • body is pale, weak and nervous />
  • Anemia can cause serious breathing difficulties />
  • Jaundice />
  • Growth retardation

  • />
  • distended stomach due to enlarged liver and spleen />
  • Changes in bone formation face, cheek and jaw abnormalities (late sign)

    Treatment
    />

  • Patients should undergo continuous blood transfusion every month
    />
  • continuous blood transfusion will result in accumulation of iron in vital organs of the body such as liver, heart and endocrine glands that eventually damage the affected organ />
  • excess iron removal treatment needs to be done with Desferrioxamine injection />
  • bone marrow transplant if suitable donor among family />

    Thalassaemia Screening
    /> Screening for thalassemia blood test may be conducted at all clinics and hospitals, whether government or private sector.

    Take the blood test to check the status of your disease.

    thalassemia patients require blood transfusions every month. Without proper treatment, several complications can occur and usually they will die in the teens.

    Thalassaemia Association of Malaysia />
    /> Association Project Malaysia to link patients with thalassemia, thalassemia, their parents and guardians with members of marginalized communities (eg rural communities). The aim is to increase public knowledge about the disease, creating an interactive two-way relationship by creating a database to facilitate research and policy development.

    /> Prevention

  • Undergo blood screening tests for those with a family history of thalassemia />
  • should be open and talk about it with your partner if you want
    married />
  • If both partners carry thalassemia features, they should consult with the attending counseling.
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